PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 15057676

Diagnostic laparoscopy.

J L Parra·K R Reddy
View original source ↗Export metadata ↓

Abstract

Since the early part of the 20th century, diagnostic laparoscopy has become an important tool in the armamentarium of surgeons and gastroenterologists alike. Its indications have expanded from initial attempts at tamponading internal hemorrhage to avoidance of unnecessary laparotomies with accurate staging of malignancies, treatment of a multitude of intra-abdominal pathologies, and even as a resource for evaluating blunt abdominal trauma and chronic abdominal pain. Its accuracy has been demonstrated in the evaluation of chronic liver diseases, in comparison with other diagnostic modalities. Many further technical advances have been introduced in recent years. Gastroenterology training programs should include formal diagnostic laparoscopy training as part of their curriculum.

Explore related subjects

Abdominal NeoplasmsClinical Trials as TopicHumansLaparoscopyLiver DiseasesRoboticsJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

J L Parra, K R Reddy. 2004. Diagnostic laparoscopy.. https://doi.org/10.1055/s-2004-814347

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2007

Response to vinorelbine and low-dose cyclophosphamide chemotherapy in two patients with desmoplastic small round cell tumor.

We report two cases of abdominal desmoplastic small round cell tumor (DSRCT) that showed a clinical response to the vinorelbine/low-dose cyclophosphamide combination that has been claimed to be effective for rhabdomyosarcoma. This observation may prompt further investigation into the activity of such a regimen in DSRCT patients with recurrent or refractory disease, with a view to a possible future role as maintenance therapy in controlling minimal residual disease in patients who achieve complete remission with intensive induction multimodality therapy.

Abdominal Neoplasms↗
PubMed2007

Desmoplastic small round cell tumor in childhood: the St. Jude Children's Research Hospital experience.

BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is a rare, primarily intra-abdominal tumor that has a poor outcome with current therapies. PROCEDURE: We retrospectively reviewed patient characteristics, presenting symptoms, tumor pathology, treatment, and outcome of 11 pediatric patients with DSRCT at our institution. RESULTS: The cohort included 1 female and 10 male patients. Median age at diagnosis was 14 years (range 5-21 years). In eight (73%) patients, the primary tumor was abdominal or pelvic, and in one patient each, it was submental, mediastinal, and paratesticular. Nine (82%) patients had metastatic disease. All tumors showed polyphenotypic differentiation by immunohistochemistry. The EWS-WT1 transcript was detected in six of seven tumors tested. One tumor showed rhabdomyoblastic differentiation after therapy. All patients received chemotherapy; eight underwent surgical resection, seven received primary site radiation, and four received myeloablative chemotherapy with stem-cell support. Three (27%) patients are alive 23 months, 8 years, and 10 years from diagnosis. Two died of treatment-related toxicity, six died of disease. None of the patients in whom surgery and initial chemotherapy failed to induce complete remission survived. CONCLUSIONS: DSRCT is an aggressive malignancy that does not respond well to contemporary treatments, and patients who do not enter complete remission after initial chemotherapy and surgery appear to have a particularly dismal outcome. Patients with localized extra-abdominal disease have a better prognosis, most likely due to increased feasibility of resection. Better understanding of molecular and genetic mechanisms of tumorigenesis and treatment-related changes may contribute to development of more effective therapy for DSRCT.

Abdominal Neoplasms↗
PubMed2006

Atypical abdominal paediatric lymphangiomatosis: diagnosis aided by diffusion-weighted MRI.

We report a 4-year-old child with a mesenteric mass, which on ultrasound, CT and conventional MRI appeared solid, raising lymphoma as a possible diagnosis. Diffusion weighted MRI (DW-MRI), however, suggested a low-cellularity lesion, making lymphoma less likely. Biopsy confirmed lymphangioma. DW-MRI may be a useful adjunct to conventional imaging, even in the abdomen.

Abdominal Neoplasms↗