Visualization of multiple genome annotations and alignments with the K-BROWSER.

Kushal Chakrabarti; Lior Pachter

doi:10.1101/gr.1957004

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Visualization of multiple genome annotations and alignments with the K-BROWSER.

Kushal Chakrabarti·Lior Pachter

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Abstract

We introduce a novel genome browser application, the K-BROWSER, that allows intuitive visualization of biological information across an arbitrary number of multiply aligned genomes. In particular, the K-BROWSER simultaneously displays an arbitrary number of genomes both through overlaid annotations and predictions that describe their respective characteristics, and through the multiple alignment that describes their global relationship to one another. The browsing environment has been designed to allow users seamless access to information available in every genome and, furthermore, to allow easy navigation within and between genomes. As of the date of publication, the K-BROWSER has been set up on the human, mouse, and rat genomes.

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Animals Computational Biology Computer Graphics Conserved Sequence Genome Genome, Human Humans Mice Rats Sequence Alignment Sequence Homology, Nucleic Acid Software Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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Kushal Chakrabarti, Lior Pachter. 2004. Visualization of multiple genome annotations and alignments with the K-BROWSER.. https://doi.org/10.1101/gr.1957004

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