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PubMed · 15088508

[The difficult years at home...].

Abstract

Patients suffering from dementia are at risk of developing some behavior problems during the evolution of the disease. Therefore, it seems important to rule out, from the outset, all physical, psychiatric, metabolic or pharmacological causes in every cognitively impaired patient with disruptive behavior. Before using any medication to treat the patient, it is advisable to attempt a non pharmacological approach. This article offers some advice to the benefit of the caregivers faced with their close ones' behavioral problems. In spite of the best non pharmacological approach, medication can be necessary in order to control and monitor the disruptive behavior. It is imperative to have a thorough knowledge of the psychotropic medications, their impact and possible side effects.

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BibTeXRIS

Francine Vézina, Guy Frenette, Céline Lefebvre. 2003. [The difficult years at home...].. https://pubmed.ncbi.nlm.nih.gov/15088508/

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PURPOSE: Pharmacology of atypical antipsychotics and the clinical implications are reviewed. SUMMARY: Psychiatric disorders, such as schizophrenia and bipolar disorder, are often associated with poor outcomes. Atypical antipsychotics have become the standard of care for these disorders, and multiple agents have demonstrated efficacy for both acute and maintenance therapy. As a result of their differential pharmacologic properties, atypical antipsychotics have diverse clinical profiles, resulting in different liabilities for specific adverse events. These effects can, in turn, have an adverse impact on patient functionality, adherence to therapy, and overall health. CONCLUSION: Atypical antipsychotics have distinct pharmacological profiles which result in clinically meaningful differences in adverse effects. Clinicians should have a wide choice of agents available with which to optimize outcomes in the majority of patients with psychiatric disorders.

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