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PubMed · 1509498

What is tityustoxin?

E C Arantes·S V Sampaio·C A Vieira·J R Giglio
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Abstract

Tityus serrulatus scorpion venom was fractionated by gel filtration affording two heterogeneous toxic fractions, T1 and T2; the latter was further fractionated by ion-exchange chromatography. The fraction of T2 eluted with 0.15 M ammonium acetate buffer, originally named 'tityustoxin', was shown to be a pool of several proteins. One of them, TsTX, as well as T1, was also named 'tityustoxin'. The major and perhaps most potent toxin of the venom, gamma-toxin, was eluted with 0.30 M buffer as a highly purified protein and shown to be different from TsTX. gamma-Toxin is contained in both T1 and T2.

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Chromatography, GelNeurotoxinsScorpion VenomsJournal ArticleResearch Support, Non-U.S. Gov't

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BibTeXRIS

E C Arantes, S V Sampaio, C A Vieira, J R Giglio. 1992. What is tityustoxin?. https://doi.org/10.1016/0041-0101(92)90015-w

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