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PubMed · 15098061

Systems for regulated or tissue-specific gene expression.

Gaetano Romano
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Abstract

The achievement of efficient regulation and/or tissue-specific gene expression is one of the major goals for gene therapists. A number of inducible systems and tissue-specific promoters are currently available. Studies in vitro and in vivo have shown promising results in controlling gene expression. However, the achievement of efficient gene regulation in patients is still an open question. This review describes the main inducible systems and tissue-specific promoters in view of their potential therapeutic applications.

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AnimalsAnimals, Genetically ModifiedCells, CulturedDrug Evaluation, PreclinicalGene Expression RegulationGene Transfer TechniquesGenetic TherapyJournal ArticleReview

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Gaetano Romano. 2004. Systems for regulated or tissue-specific gene expression.. https://doi.org/10.1358/dnp.2004.17.2.829040

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