PubMed · 15101359
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Linda Bren. Joint replacement: an inside look.. https://pubmed.ncbi.nlm.nih.gov/15101359/
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Polymethylmethacrylate (PMMA) bone cement serves as the primary fixation material between bone and the prosthetic component in cemented total hip arthroplasty. In vivo degradation of bone cement may lead to a decrease in mechanical properties of PMMA and result in aseptic loosening. However, other factors such as porosity and location of the cement relative to the bone implant interface may also contribute to mechanical behavior in vivo. This study investigated the mechanical properties of Simplex cement retrieved from 43 patients undergoing revision total hip arthroplasty. The time in vivo was between 1 month and 27 years. The variables studied included fracture toughness (KIC), porosity, molecular weight, time in vivo of the cement, and relative in vivo location of the cement with respect to the implant and bone. KIC did not correlate with time in vivo of the samples or with molecular weight. This suggests that time in vivo may not be the limiting factor in the mechanical integrity of the bone cement, A significant and inverse relationship was found between porosity and KIC. This implies that porosity is the most important factor in the mechanical behavior of bone cement during in vivo use.
The irregularity of individual wear patterns of total hip prostheses seen during patient followup may result partially from differences in radiographic projection of the components between radiographs. A method to adjust for this source of error would increase the value of individual wear curves. We developed and tested a method to correct for this source of error. The influence of patient position on validity of wear measurements was investigated with controlled manipulation of a cadaveric pelvis. Without correction, the error exceeded 0.2 mm if differences in cup projection were as small as 5 degrees. When using the described correction method, cup positioning differences could be greater than 20 degrees before introducing an error exceeding 0.2 mm. For followup of patients in clinical practice, we recommend using the correction method to enhance accuracy of the results.
The outcome of a cemented hip arthroplasty is partly dependent on the type of cement which is used. The production of an interface gap between the stem and the cement mantle as a result of shrinkage of the cement, may be a factor involved. Palacos R, Palacos LV (both with gentamicin), CMW 1, CMW 2, CMW Endurance (CMWE) and Simplex were prepared under vacuum and allowed to cure overnight in similar cylinders. The next day this volume was determined by the displacement of water. Shrinkage varied between 3.82% and 7.08% with CMWE having the lowest and Palacos LV the highest. This could be a factor to consider when choosing a cement for a shape-closed stem.