Protein function from sequence and structure data.

Francisco S Domingues; Thomas Lengauer

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PubMed · 15130830

Protein function from sequence and structure data.

Francisco S Domingues·Thomas Lengauer

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Abstract

With the large amount of genomics and proteomics data that we are confronted with, computational support for the elucidation of protein function becomes more and more pressing. Many different kinds of biological data harbour signals of protein function, but these signals are often concealed. Computational methods that use protein sequence and structure data can be used for discovering these signals. They provide information that can substantially speed up experimental function elucidation. In this review we concentrate on such methods.

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Amino Acid Sequence Conserved Sequence Databases, Protein Molecular Sequence Data Proteins Sequence Alignment Sequence Analysis, Protein Sequence Homology, Amino Acid Structure-Activity Relationship Journal Article Review

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Francisco S Domingues, Thomas Lengauer. 2003. Protein function from sequence and structure data.. https://pubmed.ncbi.nlm.nih.gov/15130830/

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