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PubMed · 15137735

Bio-bar-code-based DNA detection with PCR-like sensitivity.

Jwa-Min Nam·Savka I Stoeva·Chad A Mirkin
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Abstract

Novel two-component oligonucleotide-modified nanoparticle probes have been designed and used in a bio-bar-code assay with a 500 zeptomolar target DNA sensitivity limit.

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DNADNA ProbesGoldMagneticsMicrospheresNanotechnologyNucleic Acid Amplification TechniquesOligonucleotidesReverse Transcriptase Polymerase Chain ReactionSequence Analysis, DNAJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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Jwa-Min Nam, Savka I Stoeva, Chad A Mirkin. 2004-05-19. Bio-bar-code-based DNA detection with PCR-like sensitivity.. https://doi.org/10.1021/ja049384%2B

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