[Vitamin E and apoptosis].

G V Petrova; A A Kapralov; G V Donchenko

PubMed · 15143514

[Vitamin E and apoptosis].

Abstract

The literature data concerning the participation of tocopherol in apoptosis are discussed. Acting as antioxidant this vitamin exerts a complex effect on apoptosis mechanisms. Its action on this process is caused by involvement of some different mechanisms transducing the apoptotic signal. Among them are caspase and Fas-receptor activation, sphingosine metabolism, processes carried out in nuclei and mitochondria and signal transduction pathways. The specific mechanisms connected with interaction of this vitamin with tocopherol-binding proteins may be also involved in this vitamin action.

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Animals Antioxidants Apoptosis Calcium Signaling Second Messenger Systems Vitamin E English Abstract Journal Article Review

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G V Petrova, A A Kapralov, G V Donchenko. [Vitamin E and apoptosis].. https://pubmed.ncbi.nlm.nih.gov/15143514/

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