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The ever-increasing complexities of the exon junction complex.

Thomas Ø Tange·Ajit Nott·Melissa J Moore
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Abstract

Over the past decade many studies have revealed a complex web of interconnections between the numerous steps required for eukaryotic gene expression. One set of interconnections link nuclear pre-mRNA splicing and the subsequent metabolism of the spliced mRNAs. It is now apparent that the means of connection is a set of proteins, collectively called the exon junction complex, which are deposited as a consequence of splicing upstream of mRNA exon-exon junctions.

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AnimalsCell NucleusExonsHumansProtein BiosynthesisRNA PrecursorsRNA SplicingRNA, MessengerSpliceosomesJournal ArticleReview

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Thomas Ø Tange, Ajit Nott, Melissa J Moore. 2004. The ever-increasing complexities of the exon junction complex.. https://doi.org/10.1016/j.ceb.2004.03.012

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