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PubMed · 15170455

Fusion has found its calcium sensor.

Jacopo Meldolesi·Evelina Chieregatti
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Abstract

Synaptic vesicle exocytosis, a finely tuned process that results in rapid neurotransmitter release, is still not fully understood. Studies in a simple reconstituted lipid bilayer system have now definitively demonstrated that synaptotagmin has a key role in calcium-mediated exocytosis and have also revealed additional aspects of exocytic fusion.

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AnimalsCalcium SignalingCalcium-Binding ProteinsExocytosisHumansMembrane FusionMembrane GlycoproteinsMembrane LipidsModels, BiologicalNerve Tissue ProteinsSynaptic TransmissionSynaptic VesiclesSynaptotagminsNews

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Jacopo Meldolesi, Evelina Chieregatti. 2004. Fusion has found its calcium sensor.. https://doi.org/10.1038/ncb0604-476

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