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PubMed · 15175499

Breaking in a new function for casein kinase 2.

Julio C Morales·Phillip B Carpenter
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Abstract

DNA damage response mechanisms help ensure the fidelity of chromosomal transmission, and the failure of such mechanisms might lead to premature aging and cancer. A new report has established that casein kinase 2 (CK2), a protein that functions in diverse cellular processes, controls the activity of the DNA repair protein XRCC1. These results indicate that CK2 is a key participant in the cellular response to DNA damage.

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AnimalsCasein Kinase IIDNA RepairDNA-Binding ProteinsHumansPhosphorylationProtein Serine-Threonine KinasesX-ray Repair Cross Complementing Protein 1Journal ArticleReview

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Julio C Morales, Phillip B Carpenter. 2004-06-02. Breaking in a new function for casein kinase 2.. https://doi.org/10.1126/sageke.2004.22.pe24

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