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PubMed · 15180615

Risk behaviours and benign prostatic hyperplasia.

D Kang·G L Andriole·R C Van De Vooren·D Crawford·D Chia·D A Urban·D Reding·W-Y Huang·R B Hayes
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Abstract

OBJECTIVE: To identify risk factors for benign prostatic hyperplasia (BPH). SUBJECTS AND METHODS: Medical history data, including reported urological conditions and treatments, and risk factor data were collected from 34 694 participants in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, a randomized controlled trial designed to evaluate methods for the early detection of cancer. RESULTS: Asian men had the lowest risks (odds ratio, 95% confidence interval) for nocturia (0.7, 0.5-0.9), physician-diagnosed BPH (0.3, 0.2-0.5) and transurethral prostatectomy (TURP, 0.2, 0.1-0.6), while risks for Whites and Blacks were similar for most measures of BPH. Greater alcohol intake was associated with decreased nocturia (P trend = 0.002), BPH (P trend < 0.001) and TURP (P trend < 0.001). Current tobacco use was associated with decreased nocturia (0.8, 0.7-0.9), BPH (0.7, 0.6-0.8) and TURP (0.6, 0.4-0.8) but dose-response patterns were weak. CONCLUSION: Asian-Americans have the lowest risk of clinical BPH. Alcohol and possibly cigarettes are related to a lower risk for BPH.

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Age DistributionAgedAlcohol DrinkingAnti-Inflammatory Agents, Non-SteroidalBlack PeopleHumansMaleMiddle AgedProstatic HyperplasiaRisk FactorsSmokingTransurethral Resection of ProstateUrination DisordersWhite PeopleClinical TrialJournal ArticleRandomized Controlled Trial

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D Kang, G L Andriole, R C Van De Vooren, D Crawford, D Chia, D A Urban, D Reding, W-Y Huang, R B Hayes. 2004. Risk behaviours and benign prostatic hyperplasia.. https://doi.org/10.1111/j.1464-410x.2004.04839.x

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