Drosophila development: RNA interference ab ovo.

Marina Chekulaeva; Anne Ephrussi

doi:10.1016/j.cub.2004.05.036

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Drosophila development: RNA interference ab ovo.

Marina Chekulaeva·Anne Ephrussi

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Abstract

A novel protein required for RNA interference in Drosophila, Armitage, was identified in a screen for genes involved in embryonic axis formation. In armitage mutants, oocyte polarity and the regulation of oskar mRNA translation are impaired, suggesting that RNA silencing regulates the first steps of Drosophila development.

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Animals Body Patterning Cell Polarity Drosophila Drosophila Proteins Female Oocytes Oogenesis RNA Helicases RNA Interference RNA, Messenger RNA, Small Interfering RNA-Induced Silencing Complex Journal Article Review

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Marina Chekulaeva, Anne Ephrussi. 2004-06-08. Drosophila development: RNA interference ab ovo.. https://doi.org/10.1016/j.cub.2004.05.036

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