Multipoint recognition of basic proteins at a membrane model.

R Zadmard; M Arendt; T Schrader

doi:10.1021/ja049191m

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Multipoint recognition of basic proteins at a membrane model.

R Zadmard·M Arendt·T Schrader

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Abstract

Cell surface recognition achieves high efficiency and specificity because of its polyvalent nature. A biomimetic model has been designed, which consists of a stearic acid monolayer with embedded calixarene tetraphosphonate receptor molecules. This system is able to distinguish between proteins of varying pI at nanomolar concentrations.

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Calixarenes Lipid Metabolism Lipids Membrane Proteins Models, Molecular Polycyclic Compounds Stearic Acids Surface Properties Journal Article Research Support, Non-U.S. Gov't

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R Zadmard, M Arendt, T Schrader. 2004-06-30. Multipoint recognition of basic proteins at a membrane model.. https://doi.org/10.1021/ja049191m

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