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PubMed · 15215404

CD-Search: protein domain annotations on the fly.

Aron Marchler-Bauer·Stephen H Bryant
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Abstract

We describe the Conserved Domain Search service (CD-Search), a web-based tool for the detection of structural and functional domains in protein sequences. CD-Search uses BLAST(R) heuristics to provide a fast, interactive service, and searches a comprehensive collection of domain models. Search results are displayed as domain architecture cartoons and pairwise alignments between the query and domain-model consensus sequences. Search results may be visualized in further detail by embedding the query sequence into multiple alignment displays and by mapping onto three-dimensional molecular graphic displays of known structures within the domain family. CD-Search can be accessed at http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi.

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Amino Acid SequenceComputer GraphicsConsensus SequenceInternetProtein Structure, TertiaryProteinsSequence AlignmentSequence Analysis, ProteinSoftwareTime FactorsUser-Computer InterfaceJournal Article

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Aron Marchler-Bauer, Stephen H Bryant. 2004-07-01. CD-Search: protein domain annotations on the fly.. https://doi.org/10.1093/nar%2Fgkh454

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