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Mitoxantrone as a potential therapy for primary progressive multiple sclerosis.

Olaf Stüve·Mariko Kita·Daniel Pelletier·Robert J Fox·Jerome Stone·Donald E Goodkin·Scott S Zamvil
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Abstract

Mitoxantrone (Novantrone) was the first drug approved in western Europe and North America for treatment of secondary progressive multiple sclerosis (SPMS) and progressive relapsing MS (PRMS). Pharmacological properties of mitoxantrone, its role in SPMS, the study rational and design of an ongoing multi-centre, double blind, randomized, placebo-controlled phase 2 trial will be outlined in this article.

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HumansImmunosuppressive AgentsMitoxantroneMultiple Sclerosis, Chronic ProgressiveJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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BibTeXRIS

Olaf Stüve, Mariko Kita, Daniel Pelletier, Robert J Fox, Jerome Stone, Donald E Goodkin, Scott S Zamvil. 2004. Mitoxantrone as a potential therapy for primary progressive multiple sclerosis.. https://doi.org/10.1191/1352458504ms1032oa

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