Codon usage in Giardia lamblia.

S Char; M J Farthing

doi:10.1111/j.1550-7408.1992.tb04865.x

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PubMed · 1522548

Codon usage in Giardia lamblia.

S Char·M J Farthing

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Abstract

A codon usage table for the intestinal parasite Giardia lamblia was generated by analysis of the nucleotide sequences of eight genes comprising 3,135 codons. Codon usage revealed a biased use of synonymous codons with a preference for NNC codons (42.1%). The codon usage of G. lamblia more closely resembles that of the prokaryote Halobacterium halobium (correlation coefficient r = 0.73) rather than that of other eukaryotic protozoans, i.e. Trypanosoma brucei (r = 0.434) and Plasmodium falciparum (r = -0.31). These observations are consistent with the view that G. lamblia represents the first line of descent from the ancestral cells that first took on eukaryotic features.

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Animals Codon Eukaryotic Cells Giardia lamblia Prokaryotic Cells Comparative Study Journal Article Research Support, Non-U.S. Gov't

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S Char, M J Farthing. Codon usage in Giardia lamblia.. https://doi.org/10.1111/j.1550-7408.1992.tb04865.x

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