The mouse "tool box" for meiotic studies.

T Ashley

doi:10.1159/000078186

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The mouse "tool box" for meiotic studies.

T Ashley

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Abstract

Besides availability, there are numerous advantages to using mice for meiotic studies: (1) techniques exist for enriching the population of spermatocytes at particular meiotic stages; (2) spermatogenesis in mice is highly synchronized and testis sections afford a highly accurate method of staging meiotic events; (3) knock-out mice provide a rich source of meiotic mutants. Coupled with antibody localization techniques these tools, singularly and in combination, provide multiple means of temporally and physically dissecting meiosis.

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Animals Immunologic Techniques Intracellular Signaling Peptides and Proteins Male Meiosis Mice Mice, Knockout Models, Biological Nod2 Signaling Adaptor Protein Spermatocytes Synaptonemal Complex Testis Vitamin A Deficiency Journal Article

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T Ashley. 2004. The mouse "tool box" for meiotic studies.. https://doi.org/10.1159/000078186

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