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Exercise training improves cardiac function postinfarction: special emphasis on recent controversies on na+/ca2+ exchanger.

Joseph Y Cheung·Jianliang Song·Lawrence I Rothblum·Xue-Qian Zhang
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Abstract

Exercise training instituted after myocardial infarction improves many steps involved in cardiac excitation-contraction coupling. Focusing on Na/Caexchange, current controversies regarding whether it mediates Cainflux during an action potential, whether it is increased or decreased in disease models, whether protein kinase A alters its activity, and whether exercise training affects its function are reviewed. Finally, a novel target for exercise training in the heart is suggested.

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AnimalsCalciumCell SizeCyclic AMP-Dependent Protein KinasesDose-Response Relationship, DrugExerciseHumansMyocardial InfarctionMyocytes, CardiacPhysical Conditioning, AnimalRatsSodium-Calcium ExchangerJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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Joseph Y Cheung, Jianliang Song, Lawrence I Rothblum, Xue-Qian Zhang. 2004. Exercise training improves cardiac function postinfarction: special emphasis on recent controversies on na+/ca2+ exchanger.. https://doi.org/10.1097/00003677-200407000-00002

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