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Creating a stem cell donor: a case study in reproductive genetics.

Jeffrey P Kahn·Anna C Mastroianni
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Abstract

During the nearly 10 years since its introduction, preimplantation genetic diagnosis (PGD) has been used predominantly to avoid giving birth to a child with identified genetic disease. Recently, PGD was used by a couple not only to test IVF-created embryos for genetic disease, but also to test for a nondisease trait related to immune compatibility with a child in the family in need of an hematropoetic stem cell transplant. This article describes the case, raises some ethical and policy issues, highlights gaps in U.S. policy, and finally makes some recommendations for addressing advancing genetic and reproductive technologies.

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Advisory CommitteesDirected Tissue DonationEmbryo DispositionEmbryo TransferEthical AnalysisEthical ReviewFanconi AnemiaFertilization in VitroFetal BloodGenetic TestingHistocompatibilityHumansInfant, NewbornMotivationParentsPreimplantation DiagnosisPublic PolicyReproductionSiblingsSocial Control, FormalStem Cell TransplantationUnited StatesAnalytical ApproachGenetics and ReproductionCase ReportsJournal Article

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Jeffrey P Kahn, Anna C Mastroianni. 2004. Creating a stem cell donor: a case study in reproductive genetics.. https://doi.org/10.1353/ken.2004.0017

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