Second messenger signalling in olfaction.

H Breer; I Boekhoff

doi:10.1016/0959-4388(92)90177-m

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Second messenger signalling in olfaction.

H Breer·I Boekhoff

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Abstract

The primary reactions of the chemo-electrical signal transduction pathway in olfactory receptor neurons are mediated by two alternative second messengers, cAMP and inositol 1,4,5-trisphosphate. The rapid and transient intracellular signalling is terminated by the action of negative-feedback loops which uncouple the reaction cascades (desensitization). Recent evidence suggests that secondary reactions in olfaction (adaptation) may also be controlled by second messengers.

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H Breer, I Boekhoff. 1992. Second messenger signalling in olfaction.. https://doi.org/10.1016/0959-4388(92)90177-m

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