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Optical projection tomography.

James Sharpe
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Abstract

Optical projection tomography is a new approach for three-dimensional (3-D) imaging of small biological specimens. It fills an imaging gap between MRI and confocal microscopy, being most suited to specimens that are from 1 to 10 mm across. The tomographic principles of optical projection tomography (OPT) are explained, its most important applications in biomedical research explored, and comparisons drawn of its pros and cons compared to a number of alternative imaging technologies.

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AnimalsGene ExpressionHumansImage Processing, Computer-AssistedMicroscopy, ConfocalTomography, OpticalJournal ArticleResearch Support, Non-U.S. Gov'tReview

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James Sharpe. 2004. Optical projection tomography.. https://doi.org/10.1146/annurev.bioeng.6.040803.140210

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