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PubMed · 15262402

Unexpected conserved non-coding DNA blocks in mammals.

Daniel J Gaffney·Peter D Keightley
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Abstract

The significance of non-coding DNA is a longstanding riddle in the study of molecular evolution. Using a comparative genomics approach, Dermitzakis and colleagues have recently shown that at least some non-coding sequence, frequently ignored as meaningless noise, might bear the signature of natural selection. If functional, it could mark a turning point in the way we think about the evolution of the genome.

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AnimalsComputational BiologyConserved SequenceDNA, IntergenicEvolution, MolecularGenomicsHumansRegulatory Sequences, Nucleic AcidSequence Analysis, DNAJournal Article

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Daniel J Gaffney, Peter D Keightley. 2004. Unexpected conserved non-coding DNA blocks in mammals.. https://doi.org/10.1016/j.tig.2004.06.011

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