Pattern formation and fluctuation-induced transitions in protein crystallization.

Gregoire Nicolis; Vasileios Basios; Catherine Nicolis

doi:10.1063/1.1687339

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Pattern formation and fluctuation-induced transitions in protein crystallization.

Gregoire Nicolis·Vasileios Basios·Catherine Nicolis

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Abstract

A kinetic model of protein crystallization accounting for the nucleation stage, the growth and competition of solid particles and the formation of macroscopic patterns is developed. Different versions are considered corresponding successively, to a continuous one-dimensional crystallization reactor, a coarse grained two-box model and a model describing the evolution of the space averaged values of fluid and solid material. The analysis brings out the high multiplicity of the patterns. It provides information on their stability as well as on the kinetics of transitions between different states under the influence of the fluctuations.

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Binding Sites Computer Simulation Crystallization Kinetics Models, Chemical Models, Molecular Multiprotein Complexes Phase Transition Protein Binding Protein Conformation Proteins Journal Article Research Support, Non-U.S. Gov't

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Gregoire Nicolis, Vasileios Basios, Catherine Nicolis. 2004-04-22. Pattern formation and fluctuation-induced transitions in protein crystallization.. https://doi.org/10.1063/1.1687339

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