[Etoricoxib (Arcoxia)].

P Leclercq; M G Malaise

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PubMed · 15270001

[Etoricoxib (Arcoxia)].

P Leclercq·M G Malaise

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Abstract

Etoricoxib (Arcoxia) is a novel non steroidal anti-inflammatory drug (NSAID) that selectively inhibits the inducible form of cyclo-oxygenase (COX), COX-2. Etoricoxib has a higher COX-1/COX-2 selectivity ratio than the other COX-2-selective NSAIDs as rofecoxib, valdecoxib or celecoxib. Tablets of 60, 90 and 120 mg are available. The recommended dosage of etoricoxib is 60 mg/day for osteoarthritis, 90 mg/day for rheumatoid arthritis and 120 mg/day for acute gouty arthritis. Etoricoxib's efficacy has been widely studied in comparative studies, showing the same efficacy as non-COX-2 selective NSAID, with fewer gastro-intestinal adverse effects.

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Administration, Oral Anti-Inflammatory Agents, Non-Steroidal Arthritis, Gouty Arthritis, Rheumatoid Cyclooxygenase 2 Etoricoxib Humans Isoenzymes Membrane Proteins Osteoarthritis Prostaglandin-Endoperoxide Synthases Pyridines Sulfones Journal Article Review

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P Leclercq, M G Malaise. 2004. [Etoricoxib (Arcoxia)].. https://pubmed.ncbi.nlm.nih.gov/15270001/

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