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PubMed · 15279733

Multiple sclerosis in children.

M Tardieu·Y Mikaeloff
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Abstract

Multiple sclerosis can develop during childhood, even among children under 10 years of age, and the initial diagnosis can be difficult. A first demyelinating event in children may be an episode of monophasic acute disseminated encephalomyelitis or a first episode of a macrophage activation syndrome, angiitis affecting the central nervous system or MS. The risk of developing MS is lower if: the child is younger than 10 years old; onset is associated with severely altered consciousness; presentation is polysymptomatic; or there are large and poorly limited lesions of the white matter. MS in children probably has a slightly better outcome than MS in adults. Initial treatment mainly relies on methylprednisolone, and there is little information on the results of beta interferon treatment in children with MS.

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M Tardieu, Y Mikaeloff. 2004. Multiple sclerosis in children.. https://pubmed.ncbi.nlm.nih.gov/15279733/

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