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PubMed · 15320558

Libman-Sacks endocarditis and oral anticoagulation.

Fabiano Almeida Brito·Magali L M C Tófani·Fábio Avila Tófani·Adriana Maria Kakehasi·Cristina Costa Duarte Lanna·Marco Antonio Parreiras Carvalho
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Abstract

The patient is a 34-year-old female with systemic lupus erythematosus and secondary antiphospholipid antibody syndrome, who evolved with convulsive crises, partially controlled with an anticonvulsant, and auscultation of a cardiac murmur, whose investigation showed the presence of a mitral valve vegetation. Once the diagnosis of Libman-Sacks endocarditis was established, therapy with warfarin sodium was initiated, and, after 6 months of oral anticoagulation, the patient had total control of the convulsive crises and the valvular vegetation disappeared on echocardiography. This study discusses the occurrence of Libman-Sacks endocarditis in systemic lupus erythematosus, its association with antiphospholipid antibody syndrome, and the anticoagulant therapy. A literature review is also provided.

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Administration, OralAdultAnticoagulantsAntiphospholipid SyndromeEchocardiography, TransesophagealEndocarditisFemaleHumansLupus Erythematosus, SystemicMitral ValveWarfarinCase ReportsJournal ArticleReview

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BibTeXRIS

Fabiano Almeida Brito, Magali L M C Tófani, Fábio Avila Tófani, Adriana Maria Kakehasi, Cristina Costa Duarte Lanna, Marco Antonio Parreiras Carvalho. 2004. Libman-Sacks endocarditis and oral anticoagulation.. https://doi.org/10.1590/s0066-782x2004000400009

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