PubMed · 15321569
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G O'Sullivan, A Shennan. 2002. Labour--a gastronomic experience!. https://doi.org/10.1054/ijoa.2001.0925
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Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing the risk of overinterpreting nontumour or nonactionable genomic alterations.