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Screening for post-miscarriage psychiatric morbidity.

Ingrid H Lok·Dominic T S Lee·Shing-Kai Yip·Daniel Shek·Wing H Tam·Tony K H Chung
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Abstract

OBJECTIVE: The purpose of this study was to evaluate 12-item General Health Questionnaire (GHQ-12) in screening for psychiatric morbidity after miscarriage. STUDY DESIGN: A prospective cohort study was carried out involving 222 patients. Six weeks after miscarriage, the GHQ-12 was applied. Psychiatric "case" or "non-case" was diagnosed by the psychiatrist with use of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-III-R. The patients were computer randomized into Groups A or B. A receiver operating characteristic (ROC) curve was constructed for Group A. The optimal cutoff value of GHQ-12 was determined, and this value was applied to Group B. The test characteristics were assessed. RESULTS: Twenty-seven patients were found to be psychiatric cases. An ROC with area under curve of 0.93 (95% CI 0.87-0.99, P<.001) was constructed. The best GHQ-12 cutoff score was > or =4 in detecting psychiatric caseness. A sensitivity of 83%, specificity of 90%, positive predictive value of 50%, and negative predictive value of 98% were obtained. CONCLUSION: GHQ-12 is an effective screening tool in detecting psychiatric morbidity after miscarriage.

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Abortion, SpontaneousAdultFemaleHealth Status IndicatorsHumansMorbidityPregnancyProspective StudiesROC CurveSensitivity and SpecificitySurveys and QuestionnairesClinical TrialJournal ArticleRandomized Controlled Trial

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Ingrid H Lok, Dominic T S Lee, Shing-Kai Yip, Daniel Shek, Wing H Tam, Tony K H Chung. 2004. Screening for post-miscarriage psychiatric morbidity.. https://doi.org/10.1016/j.ajog.2004.01.003

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