CO-sensing mechanisms.

Gary P Roberts; Hwan Youn; Robert L Kerby

doi:10.1128/mmbr.68.3.453-473.2004

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PubMed · 15353565

CO-sensing mechanisms.

Gary P Roberts·Hwan Youn·Robert L Kerby

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Abstract

Carbon monoxide (CO) has long been known to have dramatic physiological effects on organisms ranging from bacteria to humans, but recently there have a number of suggestions that organisms might have specific sensors for CO. This article reviews the current evidence for a variety of proteins with demonstrated or potential CO-sensing ability. Particular emphasis is placed on the molecular description of CooA, a heme-containing CO sensor from Rhodospirillum rubrum, since its biological role as a CO sensor is clear and we have substantial insight into the basis of its sensing ability.

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Amino Acid Sequence Animals Bacteria Bacterial Proteins Carbon Monoxide Eukaryotic Cells Gene Expression Regulation Hemeproteins Humans Models, Molecular Molecular Sequence Data Signal Transduction Trans-Activators Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

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Gary P Roberts, Hwan Youn, Robert L Kerby. 2004. CO-sensing mechanisms.. https://doi.org/10.1128/mmbr.68.3.453-473.2004

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