PubMed · 15415194
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J EVANS. 1950. Case reposts; Miller.. https://doi.org/10.1037/h0059160
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Intraocular involvement in Langerhans cell histiocytosis (LCH) is rare. We describe the case of a neonate with congenital disseminated LCH involving skin, liver, spleen, and intraocular structures including uvea and retina. Early and aggressive treatment according to the LCH-II treatment protocol was administered and resulted in remission of the disease. However, despite close follow-up and additional local treatment, involvement of intraocular structures resulted in severe long-term ophthalmological sequelae including complete bilateral loss of vision.
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CASE REPORT: We report a case of ganglioglioma of the optic chiasma in an 8-year-old child who presented with gradual deterioration of vision since the age of 3 years and complete loss by 8 years. REVIEW OF LITERATURE: Intensive literature search by the authors showed only 12 cases of ganglioglioma involving the visual pathway reported so far. Report on our case is presented here along with review of literature.