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A simple solid phase diversity linker strategy using enol phosphonates.

Ian B Campbell·Jun Guo·Edward Jones·Patrick G Steel
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Abstract

Polymer bound lactam enol phosphonates can be easily generated using simple phenol on polystyrene resin. These stable, storable compounds can be released in a diversity cleavage strategy, using Suzuki cross coupling conditions, to provide 2-arylenamides in moderate to good overall yields.

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Cross-Linking ReagentsMolecular StructureOrganophosphonatesJournal ArticleResearch Support, Non-U.S. Gov't

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Ian B Campbell, Jun Guo, Edward Jones, Patrick G Steel. 2004-09-01. A simple solid phase diversity linker strategy using enol phosphonates.. https://doi.org/10.1039/b411111g

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