PubMed Health⌕ Search

PubMed · 15456984

Current issues in statistics and models for ecotoxicological risk assessment.

Abstract

A review is given on statistical and modelling issues in ecotoxicology. The issues discussed are: 1. How to estimate an (almost) no effect concentration chemicals in the laboratory. 2. Combining single-species acceptable effect levels to an acceptable effect level for a multi-species ecosystem. 3. The combined effect of exposure to several chemicals. 4. Bioavailability in the natural environment and food-web models. Most current procedures in setting standards allow the environmental concentration to be above the acceptable effect concentration for a small fraction of the species. It is shown that a considerable part of the fraction of the affected species will suffer a severe effect.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Nelly van der Hoeven. 2004. Current issues in statistics and models for ecotoxicological risk assessment.. https://doi.org/10.1023/b%3Aacbi.0000043442.05899.8c

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

An ecologic study of cancer mortality rates in Spain with respect to indices of solar UVB irradiance and smoking.

There is increasing evidence that vitamin D reduces the risk of many types of cancer. Geographic variations in cancer mortality rates in Spain are apparently linked to variations in solar ultraviolet (UV) irradiances and other factors. Cancer mortality rates for 48 continental Spanish provinces for 1978-1992 were used in linear regression analyses with respect to mortality rates for latitude (an index of solar UVB levels), skin cancer (an index of high cumulative UVB irradiance), melanoma (an index related to solar UV irradiance and several other factors) and lung cancer (an index of cumulative effects of smoking). The 9 cancers with mortality rates significantly correlated with latitude for 1 or both sexes were brain, gastric, melanoma, nonmelanoma skin cancer (NMSC), non-Hodgkin's lymphoma (NHL), pancreatic, pleural, rectal and thyroid cancer. Inverse correlations with latitude were found for laryngeal, lung and uterine corpus cancer. The 17 cancers inversely correlated with NMSC are bladder, brain, breast, colon, esophageal, gallbladder, Hodgkin's lymphoma, lung, melanoma, multiple myeloma, NHL, ovarian, pancreatic, pleural, rectal, thyroid and uterine corpus cancer. The 16 correlated with melanoma are bladder, brain, breast, colon, gallbladder, leukemia, lung, multiple myeloma, NHL, ovarian, pancreatic, pleural, prostate, rectal, renal and uterine corpus cancer. The results for lung cancer were in accordance with the literature. These results provide more support for the UVB/vitamin D/cancer hypothesis and indicate a new way to investigate the role of solar UV irradiance on cancer risk. They also provide more evidence that melanoma and NMSC have different etiologies.

Ecology↗

Data storm.

Explore the source record for details and available documents.

Ecology↗