Maintaining integrity.

Yosef Shiloh; Alan R Lehmann

doi:10.1038/ncb1004-923

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PubMed · 15459720

Maintaining integrity.

Yosef Shiloh·Alan R Lehmann

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Abstract

Research on genome stability and integrity now extends far beyond the biochemistry of DNA repair to encompass signal transduction pathways that span numerous aspects of cellular life. Derailed genomic integrity pathways can result in debilitating genetic disorders, premature ageing, predisposition to cancer and degenerative conditions. Current progress in this rapidly expanding field was the subject of an EMBO workshop, Maintenance of Genomic Integrity, that took place in June 2004 in Galway, Ireland. Top

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Animals Centrosome Chromosome Aberrations DNA Damage DNA Repair DNA Replication Genetic Diseases, Inborn Genetic Predisposition to Disease Genomic Instability Humans Neoplasms Progeria Signal Transduction Conference Proceedings Research Support, Non-U.S. Gov't

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Yosef Shiloh, Alan R Lehmann. 2004. Maintaining integrity.. https://doi.org/10.1038/ncb1004-923

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