A web-based randomisation service for clinical studies.

Abstract

The Competence Network for Acute and Chronic Leukemias is one of several networks of competence, each directed at a specific disease. Within this context, a web-based randomisation service was designed and implemented as a service to participating study groups. It provides centralised randomisation for several study centres that is independent of each of the centres. In order to minimise difficulties in using this service arising from the fact that it is only needed fairly infrequently, the user interface was kept as simple as possible. The major advantages of a web-based service lie in its "unpredictability" and its continuous availability at all times without the need for around-the-clock personnel. The experience gained with this service in the context of the Competence Network with a relatively small number of actual users may provide the basis for a more widespread application.