Pituicytoma.

Robert J Kowalski; Richard A Prayson; Marc R Mayberg

doi:10.1016/j.anndiagpath.2004.07.006

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PubMed · 15494936

Pituicytoma.

Robert J Kowalski·Richard A Prayson·Marc R Mayberg

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Abstract

Pituicytoma is a rare, low-grade neoplasm that originates in the neurohypophysis of the pituitary gland. We report the clinicopathologic features of a pituicytoma arising in a 52-year-old man who presented with a mass and panhypopituitarism, clinically suggestive of a pituitary adenoma. The tumor was marked by a proliferation of elongated cells arranged in bundles and interlacing fascicles. The tumor demonstrated positive staining with S-100 protein and glial fibrillary acid protein antibodies. The tumor did not stain with antibodies to cytokeratin, synaptophysin, chromogranin, anterior pituitary hormones, or p53. An MIB-1 labeling index of 1.1% was observed. The tumor was subtotally resected and recurred 11 months after the initial surgery. The literature on this rare tumor will be reviewed and differential diagnosis discussed.

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Biomarkers, Tumor Combined Modality Therapy Glial Fibrillary Acidic Protein Glioma Humans Immunoenzyme Techniques Ki-67 Antigen Magnetic Resonance Imaging Male Middle Aged Neoplasm Recurrence, Local Pituitary Gland, Posterior Pituitary Neoplasms Radiotherapy, Adjuvant S100 Proteins Case Reports Journal Article

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Robert J Kowalski, Richard A Prayson, Marc R Mayberg. 2004. Pituicytoma.. https://doi.org/10.1016/j.anndiagpath.2004.07.006

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