PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 1550383

Multiple invasive squamous cell carcinomas and common variable immunodeficiency.

H A Green·S Moschella
View original source ↗Export metadata ↓

Abstract

The source did not provide an abstract. Follow the original record for more information.

Explore related subjects

AgammaglobulinemiaCarcinoma, Squamous CellFemaleHumansImmunocompromised HostMiddle AgedNeoplasm InvasivenessSkin NeoplasmsCase ReportsLetter

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

H A Green, S Moschella. 1992. Multiple invasive squamous cell carcinomas and common variable immunodeficiency.. https://pubmed.ncbi.nlm.nih.gov/1550383/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Carrier detection and prenatal diagnosis of X-linked agammaglobulinemia.

We investigated the pregnant mother of a boy with X-linked agammaglobulinemia (XLA) but with no family history of immune disease. The X-inactivation pattern was found, using a methylation-sensitive probe, to be skewed in the maternal B cells but random in the polymorphonuclear cells, indicating carrier status and a 50% risk of inheritance for her male fetus. Using probes assigned to regions on either side of the XLA locus and defining RFL polymorphism, we excluded for the first time a diagnosis of XLA on a chorionic villus sample, with a risk of error less than 0.003. Immunological studies performed at the 19th week of gestation and 3 days after birth confirmed normality. Carrier detection based on the X-chromosome inactivation pattern, together with prenatal studies using probes close to the disease locus, thus permits prenatal diagnosis in families with isolated cases of XLA.

Agammaglobulinemia↗