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PubMed · 15532060

DNA codes for nanoscience.

Bruno Samorì·Giampaolo Zuccheri
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Abstract

The nanometer scale is a special place where all sciences meet and develop a particularly strong interdisciplinarity. While biology is a source of inspiration for nanoscientists, chemistry has a central role in turning inspirations and methods from biological systems to nanotechnological use. DNA is the biological molecule by which nanoscience and nanotechnology is mostly fascinated. Nature uses DNA not only as a repository of the genetic information, but also as a controller of the expression of the genes it contains. Thus, there are codes embedded in the DNA sequence that serve to control recognition processes on the atomic scale, such as the base pairing, and others that control processes taking place on the nanoscale. From the chemical point of view, DNA is the supramolecular building block with the highest informational content. Nanoscience has therefore the opportunity of using DNA molecules to increase the level of complexity and efficiency in self-assembling and self-directing processes.

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Base PairingDNANanotechnologyNucleic Acid ConformationJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Bruno Samorì, Giampaolo Zuccheri. 2005-02-11. DNA codes for nanoscience.. https://doi.org/10.1002/anie.200400652

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