LTP and LTD vary with layer in rodent visual cortex.

Nigel Daw; Yan Rao; Xue-Feng Wang; Quentin Fischer; Yupeng Yang

doi:10.1016/j.visres.2004.09.004

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LTP and LTD vary with layer in rodent visual cortex.

Nigel Daw·Yan Rao·Xue-Feng Wang·Quentin Fischer·Yupeng Yang

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Abstract

Mechanisms of plasticity in the visual cortex have been studied with long-term potentiation (LTP), long-term depression (LTD) and ocular dominance plasticity (ODP). It is now possible to compare results from these three forms of plasticity using knockout mice, and also by pharmacological manipulations. A review of the literature shows that if both LTP and LTD are completely abolished, then ODP will also be abolished. In other situations, there is little correlation. We hypothesize that this lack of correlation occurs because the mechanisms for LTP and LTD vary with layer in the visual cortex, and results show that they do.

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Animals Dominance, Ocular Long-Term Potentiation Long-Term Synaptic Depression Mice Mice, Knockout Rats Visual Cortex Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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Nigel Daw, Yan Rao, Xue-Feng Wang, Quentin Fischer, Yupeng Yang. 2004. LTP and LTD vary with layer in rodent visual cortex.. https://doi.org/10.1016/j.visres.2004.09.004

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