Radiographic and function changes after partial lung irradiation in the rat.

B J Geist; K R Trott

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PubMed · 1553621

Radiographic and function changes after partial lung irradiation in the rat.

B J Geist·K R Trott

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Abstract

The early and late changes in the right rat lung following single dose X-irradiation were studied using computerised axial tomography (CT) and noninvasive lung function tests. The biphasic response of the lung, i.e., the early pneumonitis phase, from six to ten weeks and later fibrosis starting at 18 weeks after irradiation, were both detectable by increased lung density. Whereas functional changes were prominent during the pneumonitis phase, these were only minor in the late phase.

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Animals Dose-Response Relationship, Radiation Lung Lung Diseases Male Radiation Injuries, Experimental Rats Rats, Inbred Strains Time Factors Tomography, X-Ray Computed Journal Article Research Support, Non-U.S. Gov't

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B J Geist, K R Trott. 1992. Radiographic and function changes after partial lung irradiation in the rat.. https://pubmed.ncbi.nlm.nih.gov/1553621/

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