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PubMed · 15537058

Technology evaluation: EMD-273063, EMD Lexigen.

Ion Niculescu-Duvaz
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Abstract

EMD-273063 is an antibody/cytokine fusion protein comprised of a humanized version of the murine anti-GD2 antibody 14.18 coupled to two molecules of IL-2. It is being developed by EMD Lexigen Research Center Corp (a subsidiary of Merck KGaA) and its sister company, EMD Pharmaceuticals Inc, for the potential treatment of neuroblastoma and melanoma, for which it is in preclinical and phase I clinical trials, respectively.

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AnimalsAntibodies, MonoclonalClinical Trials, Phase I as TopicDrug Evaluation, PreclinicalHumansInterleukin-2MelanomaNeuroblastomaPatents as TopicStructure-Activity RelationshipJournal Article

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Ion Niculescu-Duvaz. 2004. Technology evaluation: EMD-273063, EMD Lexigen.. https://pubmed.ncbi.nlm.nih.gov/15537058/

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