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PubMed · 15540536

[Inflammation and diabetes].

K Löbner·M Füchtenbusch
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Abstract

The focus of current diabetes research is the clarification of the pathogenetic relationships between subclinical inflammation, diabetes and arteriosclerosis. Even minimal disturbances in glucose tolerance are associated with a chronic, generalized inflammatory reaction that links components of the metabolic syndrome and contributes to the development of diabetic complications as well as to the development and progression of arteriosclerosis. The most important mediators and markers of this inflammation cascade are NF-kappaB, TNF-alpha, IL-6, CRP and PAI-1. For the treatment of subclinical inflammation, substances with anti-inflammatory properties such as statins or ACE inhibitors are of increasing importance.

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AdiponectinAngiotensin-Converting Enzyme InhibitorsAnti-Inflammatory Agents, Non-SteroidalArteriosclerosisAspirinBlood GlucoseBody WeightC-Reactive ProteinChronic DiseaseDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2ExerciseHumansHypertensionHypoglycemic AgentsHypolipidemic AgentsInflammationInflammation MediatorsInsulinInsulin ResistanceIntercellular Signaling Peptides and ProteinsMetabolic SyndromeObesityResearchRisk FactorsRosiglitazoneThiazolidinedionesComparative StudyJournal ArticleReview

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K Löbner, M Füchtenbusch. 2004-09-02. [Inflammation and diabetes].. https://pubmed.ncbi.nlm.nih.gov/15540536/

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