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Conducting international collaborative research in developing nations.

S E Geller·A Patel·V A Niak·S S Goudar·S A Edlavitch·B S Kodkany·R J Derman
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Abstract

International research partnerships bring together some of the best and the brightest in an effort to tackle global health problems. Such collaborations also pose complex challenges, such as maintaining ethical principles in the conduct of research in developing nations. In implementing a randomized clinical trial to reduce postpartum hemorrhage (PPH) during childbirth in rural India, U.S. and Indian collaborators addressed three such issues: the appropriateness of an ethical randomized controlled trial in the developing world, the inclusion of a placebo arm, and the relevance of informed consent in a semiliterate rural population.

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Administration, OralDeveloping CountriesDouble-Blind MethodEducational StatusEthics, ResearchFemaleHelsinki DeclarationHumansIndiaInformed ConsentInternational CooperationMisoprostolMulticenter Studies as TopicOxytocicsPostpartum HemorrhagePregnancyRandomized Controlled Trials as TopicRural Health ServicesRural PopulationBiomedical and Behavioral ResearchJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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S E Geller, A Patel, V A Niak, S S Goudar, S A Edlavitch, B S Kodkany, R J Derman. 2004. Conducting international collaborative research in developing nations.. https://doi.org/10.1016/j.ijgo.2004.08.019

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