Delayed emesis: moderately emetogenic chemotherapy.

Fausto Roila; David Warr; Rebecca A Clark-Snow; Maurizio Tonato; Richard J Gralla; Lawrence H Einhorn; Jorn Herrstedt

doi:10.1007/s00520-004-0700-8

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Delayed emesis: moderately emetogenic chemotherapy.

Fausto Roila·David Warr·Rebecca A Clark-Snow·Maurizio Tonato·Richard J Gralla·Lawrence H Einhorn·Jorn Herrstedt

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Abstract

Data on the incidence and efficacy of antiemetic prophylaxis against delayed emesis induced by moderately emetogenic chemotherapy are scanty. An overview of the literature has been done that showed the efficacy of dexamethasone in two of three randomized trials. Its optimal dose and duration of administration has not been defined. Only one of four randomized studies showed a statistically significant efficacy of 5-HT(3) antagonists. Finally, only weak evidence has been published on the efficacy of dopamine receptor antagonists.

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Fausto Roila, David Warr, Rebecca A Clark-Snow, Maurizio Tonato, Richard J Gralla, Lawrence H Einhorn, Jorn Herrstedt. 2004-11-12. Delayed emesis: moderately emetogenic chemotherapy.. https://doi.org/10.1007/s00520-004-0700-8

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