[VDR function in skin].

Shigeaki Kato; Yamamoto Yoko

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PubMed · 15577142

[VDR function in skin].

Shigeaki Kato·Yamamoto Yoko

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Abstract

Typical abnormalities of hereditary rickets type II patients were observed in the mice deficient of VDR with growth retardation, impaired bone formation and alopecia. Except alopecia, all of the abnormalities were rescued by dietary supplement of high minerals. Genetic mutations in the critical vitamin D biosynthesis enzyme in humans and mice also suffer rachtic phenotypes except alopecia. The function of VDR in skin will be discussed.

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25-Hydroxyvitamin D3 1-alpha-Hydroxylase Alopecia Animals Humans Hypophosphatemia, Familial Mutation Receptors, Calcitriol Vitamin D Journal Article Review

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Shigeaki Kato, Yamamoto Yoko. 2004. [VDR function in skin].. https://pubmed.ncbi.nlm.nih.gov/15577142/

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