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Inclusion complex formation between alpha-cyclodextrin and biodegradable aliphatic polyesters.

Kyung-Moo Shin·Tungalag Dong·Yong He·Yoichi Taguchi·Akihiro Oishi·Haruo Nishida·Yoshio Inoue
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Abstract

Inclusion complexes (ICs) between alpha-cyclodextrin (alpha-CD) and three kinds of biodegradable aliphatic polyesters with different sequence lengths of the monomeric repeating units poly(3-hydroxypropionate) [P(3HP)], poly(4-hydroxybutyrate) [P(4HB)] and poly(epsilon-caprolactone)(PCL) were prepared by mixing a solution of alpha-CD with that of the polymer, followed by stirring. The ICs were obtained as insoluble precipitates and characterized by FT-IR, WAXD and DSC. All measurements showed that the polymer chains of all three kinds of polyester were included into the alpha-CD cavity and formed ICs with different stoichiometries. WAXD patterns and thermal analysis indicated that these ICs possessed a channel structure and the crystallization of the polyester chains was suppressed upon inclusion into the alpha-CD cavity.

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Biodegradation, EnvironmentalCalorimetry, Differential ScanningCrystallizationHydrogen BondingMacromolecular SubstancesMagnetic Resonance SpectroscopyPolyestersSpectroscopy, Fourier Transform InfraredTemperatureX-Ray Diffractionalpha-CyclodextrinsJournal Article

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Kyung-Moo Shin, Tungalag Dong, Yong He, Yoichi Taguchi, Akihiro Oishi, Haruo Nishida, Yoshio Inoue. 2004-12-15. Inclusion complex formation between alpha-cyclodextrin and biodegradable aliphatic polyesters.. https://doi.org/10.1002/mabi.200400118

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