The cytoskeleton and mRNA localization.

R H Singer

doi:10.1016/0955-0674(92)90053-f

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The cytoskeleton and mRNA localization.

R H Singer

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Abstract

The localization of mRNA appears to facilitate protein sorting, so that proteins are synthesized in specific cellular regions. The spatial information on the mRNA may be transduced by proteins that recognize specific localizing sequences on the 3' end and then chaperone the mRNA, presumably along filaments, to its destination. Additional sequences such as poly(A), or the nascent chains of cytoskeleton-associated proteins, may then anchor mRNAs on the cytoskeleton.

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Animals Biological Transport, Active Cytoplasm Cytoskeletal Proteins Cytoskeleton Gene Expression Protein Processing, Post-Translational RNA, Messenger Journal Article Research Support, U.S. Gov't, P.H.S.Review

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R H Singer. 1992. The cytoskeleton and mRNA localization.. https://doi.org/10.1016/0955-0674(92)90053-f

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