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Update on genome completion and annotations: Protein Information Resource.

Cathy Wu·Daniel W Nebert
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Abstract

The Protein Information Resource (PIR) recently joined the European Bioinformatics Institute (EBI) and Swiss Institute of Bioinformatics (SIB) to establish UniProt--the Universal Protein Resource--which now unifies the PIR, Swiss-Prot and TrEMBL databases. The PIRSF (SuperFamily) classification system is central to the PIR/UniProt functional annotation of proteins, providing classifications of whole proteins into a network structure to reflect their evolutionary relationships. Data integration and associative studies of protein family, function and structure are supported by the iProClass database, which offers value-added descriptions of all UniProt proteins with highly informative links to more than 50 other databases. The PIR system allows consistent, rich and accurate protein annotation for all investigators.

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AnimalsComputational BiologyDatabases, ProteinGenome, HumanHumansInformation Storage and RetrievalInternetProteinsJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.Review

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Cathy Wu, Daniel W Nebert. 2004. Update on genome completion and annotations: Protein Information Resource.. https://doi.org/10.1186/1479-7364-1-3-229

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