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Nicotine augmentation for refractory obsessive-compulsive disorder. A case report.

Massimo Pasquini·Alessandra Garavini·Massimo Biondi
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Abstract

The authors present a case of obsessive-compulsive disorder (OCD) resistant to conventional treatments, which improved following nicotine augmentation administered as 4 mg chewing gum. The role of acetylcholine in the pathophysiology of OCD is not clear. The authors discuss the effect of nicotine on memory for actions.

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AcetylcholineAdultAntidepressive Agents, TricyclicClomipramineDrug ResistanceGABA AgentsHumansMaleNicotineNicotinic AgonistsObsessive-Compulsive DisorderValproic AcidCase ReportsJournal Article

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Massimo Pasquini, Alessandra Garavini, Massimo Biondi. 2005. Nicotine augmentation for refractory obsessive-compulsive disorder. A case report.. https://doi.org/10.1016/j.pnpbp.2004.08.011

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